Generic & trade name:
325-650 mg PO q4h
325-3000 mg daily in divided doses
Not to exceed 4 g/day. Do not crush enteric coated tab. Administer with food/full glass of water to minimize GI distress. For acute MI, have patient chew tablet.
Reduces inflammation and fever by inhibiting prostaglandin production
Reduces ability of blood to clot
and VITAL SIGNS
Monitor CBC, platelets, PT, BUN, serum creatinine, and liver function studies to detect abnormalities.
Monitor VS, temperature
SIDE EFFECTS and CONTRAINDICATIONS
(most common & life threatening/life threatening in ALL CAPS)
ANAPHYLAXIS and LARYNGEAL EDEMA, Salicylate Allergy/Sensitivity
Contraindicated with bleeding disorders, anticoagulant therapies like warfarin, heparin, plicamycin.
Use with caution: GI BLEEDING, ACUTE RENAL INSUFFICIENCY, ulcers, alcohol abuse, renal/hepatic disease.
Dizziness, confusion, drowziness, tinnitus, epigastric distress, nausea, abdominal pain, hepatotoxicity, vomiting, hives, rashes, Stevens-Johnson syndrome, dyspensia, anemia, hemolysis; allergic reactions: anaphylaxis, laryngeal edema.
• Assess • Administration
• Teaching • Toxicity/overdose
• IV Compatibility
Advise to report tinnitus; unusual bleeding/ bruising; black/tarry stools; or fever > 3 days.
Caution patient to avoid use of alcohol.
Sodium-restricted diet → avoid effervescent tablets or buffered-aspirin.
Advise patients if taking as prophylactic — take only prescribed dose.Use lowest effective dose/shortest period.
If patient is taking an antidepressant such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone — may bruising or bleeding, as well as blood thinners (warfarin, Coumadin), or other medication used to prevent blood clots.